Active substances: Amoxicillin
For this reason, the severity and frequency of adverse effects from amoxicillin is probably higher than reported from clinical trials. The rash can also occur in adults.
The rash is described as maculopapular or morbilliform measles-like; therefore, in medical literature, it is called "amoxicillin-induced morbilliform rash".
It starts on the trunk and can spread from there. This rash is unlikely to be a true allergic reaction and is not a contraindication for future amoxicillin usage, nor should the current regimen necessarily be stopped.
However, this common amoxicillin rash and a dangerous allergic reaction cannot easily be distinguished by inexperienced persons, so a healthcare professional is often required to distinguish between the two.
Eight hours after the first photo, individual spots have grown and begun to merge. In general, Streptococcus, Bacillus subtilis, Enterococcus, Haemophilus, Helicobacter, and Moraxella are susceptible to amoxicillin, whereas Citrobacter, Klebsiella and Pseudomonas aeruginosa are resistant to it.
Rarer adverse effects include mental changes, lightheadedness, insomnia, confusion, anxiety, sensitivity to lights and sounds, and unclear thinking.
Immediate medical care is required upon the first signs of these adverse effects. The initial phase of such a reaction often starts with a change in mental state, skin rash with intense itching often beginning in fingertips and around groin area and rapidly spreading, and sensations of fever, nausea, and vomiting.
Any other symptoms that seem even remotely suspicious must be taken very seriously. However, more mild allergy symptoms, such as a rash, can occur at any time during treatment, even up to a week after treatment has ceased.
For some people allergic to amoxicillin, the adverse effects can be fatal due to anaphylaxis. Penicillin V is indicated for the treatment of mild gram-positive infections of the throat, respiratory tract and soft tissues.
This natural penicillin is still the drug of choice for the treatment of group A streptococcal pharyngitis in patients who are not allergic to penicillin. These chemically modified penicillins have a side chain that inhibits the action of penicillinase.
The agents in this class with the best oral absorption are cloxacillin Tegopen and dicloxacillin Dynapen. These drugs should be taken one to two hours before meals. Penicillinase-resistant penicillins are primarily indicated for the treatment of skin and soft tissue infections.
Amoxicillin is more completely absorbed than ampicillin.